Blind World

Macular Degeneration.
12 to 20 Plus Introduces Eye Specific Supplement for Macular Degeneration.

April 30, 2004.

Press Release.
Market Wire.

According to a recent poll, Americans dread blindness more than any other disability. Recent studies indicate that by the year 2025, the population of people over the age of 65 in the United States will be six times higher than in 1990. The reason -- "baby boomers" are aging and overall life expectancy is increasing. Since many people diagnosed with macular degeneration are over age 55, the number of cases of macular degeneration in the U.S. will increase significantly as baby boomers age.

Said Carol Slavin, President "The market is very large, with about 50 million AMD sufferers worldwide (15 million in the U.S.) and five million new cases each year. Less than 2% of all AMD cases are treated successfully, so an urgent need exists for effective new strategies." We would anticipate significant revenues in the millions of dollars as we increase our distribution capabilities and our VisionKare™ brand becomes the "benchmark" for the industry.

The Age-Related Eye Disease Study (AREDS), a 10-year major clinical trial sponsored by the National Eye Institute, one of the Federal government's National Institutes of Health, found that high levels of antioxidants and zinc significantly reduce the risk of advanced age-related macular degeneration (AMD) and its associated vision loss. Nutraceutical Research Group' (NRG), a division of 12 to 20 Plus has developed a compelling product, VisionKare™, containing a host of eye-beneficial nutrients in addition to the recommended antioxidants and zinc. The VisionKare product contains amino acids which stabilize healthy cell membranes and enhance the rods and cones in the macular area of the retina where the greatest visual acuity occurs.

Age-related macular degeneration is the leading cause of blindness in the middle-aged and elderly. This disease is characterized by a gradual and painless deterioration of the central part of the retina that distinguishes fine visual detail. Carol Slavin, Company president says, "VisionKare's unique composition also includes L-OptiZinc®, the most potent antioxidant zinc supplement available, making the product the most complex formulation available to help stave off severe vision loss. The high level of nutrients in VisionKare are very difficult to achieve by diet alone, especially in the elderly population where diets are low in proteins and antioxidants."

Paul A. Sieving, M.D., Ph.D, director of National Eye Institute in referring to the major clinical trial, said, "This is an exciting discovery because for people at high risk for developing advanced AMD, these nutrients are the first effective treatment to slow the progression of the disease."

End of article.

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